Cortical neurons gradually attain a post-mitotic state
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چکیده
منابع مشابه
The post-mitotic state in neurons correlates with a stable nuclear higher-order structure
Neurons become terminally differentiated (TD) post-mitotic cells very early during development yet they may remain alive and functional for decades. TD neurons preserve the molecular machinery necessary for DNA synthesis that may be reactivated by different stimuli but they never complete a successful mitosis. The non-reversible nature of the post-mitotic state in neurons suggests a non-genetic...
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ژورنال
عنوان ژورنال: Cell Research
سال: 2016
ISSN: 1001-0602,1748-7838
DOI: 10.1038/cr.2016.76